The Giorgio Asproni National Archaeological Museum is located in the historic center of the city of Nuoro and represents an important cultural reference for central Sardinia. It is located in a historic nineteenth-century building that belonged to Giorgio Asproni, a Sardinian intellectual and politician of the twentieth century.

The collection includes archaeological and paleontological finds that tell the story of the territories of Barbagia and Ogliastra, from their origins to the medieval age. It is possible to admire the evidence of vertebrates from Monte Tuttavista and the Corbeddu Cave, the Palaeolithic finds and the collection of Neolithic daily life objects. This is followed by the materials of the Copper Age cultures of Filigosa, Abealzu, Monte Claro, of the Campaniforme vase and of the culture of Bonnanaro, to which the skeleton of Sisaia, found in the homonymous cave is given. The objects of the Nuragic period, the Bronze and Iron Ages come from important sites such as "Su Tempiesu" in Orune, "Sa Sedda 'e Sos Carros", in Oliena.

The collection also includes the reconstruction of the sacred source of Oliena. The exhibition itinerary ends with the medieval age and the objects from the Castello della Fava di Posada.