The Natural History Museum was founded at the end of the 19th century by Giacomo Doria, a passionate naturalist, who exhibited his collections along with those of Lorenzo Pareto and Prince Oddone of Savoy.

Subsequently, this core was enriched by acquisitions from expeditions funded by Doria and by bequests and donations. The vastness of the collected material made it necessary to transfer the museum to a building specifically designed and built at the beginning of the 20th century.

Today, the museum is the oldest in the city and certainly one of the most important in the local context. The collections are displayed in showcases equipped with informative displays about their content: a total of approximately 4 and a half million artifacts and specimens.

The exhibition is divided into 23 rooms. The journey begins in the space dedicated to Paleontology and continues with rooms exhibiting collections of high scientific value, mostly zoological. There are also sections displaying botanical specimens and collections of fossils, rocks, and minerals. Among the most notable collections are those of Mammals, Birds, and Insects.