It is located in the fourteenth-century Palazzo dei Consoli and with the Regional Museum of Ceramics it forms the urban museum circuit. The collection of the Pinacoteca is rich and diversified and, after the last restoration, the exhibition has been revised and enlarged: on the first floor the works from the local churches of San Francesco and Sant'Antonio Abate are preserved; of great artistic interest are the fresco by Pietro Vannucci known as Perugino (Father Eterno, San Romano and San Rocco), the two works by Niccolò di Liberatore known as l'Alunno (Madonna dei Consoli and Gonfalone di Sant'Antonio Abate) and the 13th century Franciscan parchment missal.

On the upper floor there is the collection of Lione Pascoli , acquired by donation in 1931, and consisting of about 40 paintings; among the works, all highly representative of Roman collecting in the early eighteenth century (minor genres are largely present, bambocciate, still lifes, landscapes, battles), canvases by Giovanni Battista Gaulli known as Baciccio, Antonio Amorosi, Francesco Trevisani, Sebastiano Conca, Francesco Graziani and Pieter Van Bloemen.