Located in the heart of Avignon, the Musée Requien is a fascinating natural history museum that takes you on a journey through the fauna and flora of the Vaucluse region. Founded in 1840 by the naturalist Esprit Requien, the museum is housed in the elegant Hôtel de Raphélis de Soissans, an 18th-century building that adds a historical touch to the museum experience.

The museum's collections include over 1.2 million specimens, including an herbarium with approximately 150,000-300,000 plants, fossils, minerals, and shells. These artifacts provide a detailed overview of local biodiversity and are also used for scientific research activities. Esprit Requien's library, with over 18,000 volumes, is a valuable resource for scholars and enthusiasts of natural sciences.