The National Museum of Palazzo Reale is located in the historic center of Pisa. The Palace, whose construction, between 1583 and 1587, is due to Francesco I de 'Medici, with the facade facing the Arno river while on the back, through two large arches, is connected on one side to the church of San Nicola and from the another to the thirteenth-century Casa delle Vedove. Currently also seat of the Superintendency, it houses the museum in the rooms of the noble floor. It documents the development over time of an identical propensity for beauty of the ruling classes, from the Medici to the bourgeois collectors of the twentieth century. In fact, the tapestries and furnishings that the Medici used to adorn the halls of the palace itself are exhibited. Among the portraits of the main exponents of the family, the notable effigies of Eleonora di Toledo, wife of Cosimo I de 'Medici by Bronzino, of Cosimo himself depicted with the grand ducal insignia, of Ferdinando de' Medici as a cardinal work of Alessandro Allori. Other monumental portraits of the grand dukes, alongside the numerous portraits by Ferretti and Tempesti of members of the Lorraine family that took over from the Medici in the government of Tuscany and of two Savoy kings, Vittorio Emanuele II and Umberto I. Of particular importance is the collection of armaments of the Gioco del Ponte, full of over 900 Lombard pieces from the 15th-18th centuries. Among the private collections received for various reasons are works attributed to Rosso Fiorentino "Rebecca al pozzo", to the very young Raphael "the Miracle of the two hanged men, part of the predella of the Triptych of San Nicola da Tolentino", by Francesco and Luigi Gioli and the very rich legacy of the surgeon Antonio Ceci with Italian and Flemish paintings, miniatures on ivory, medals, porcelain, bronzes and drawings. Among the most recent acquisitions are the paintings by Plinio Nomellini, Spartaco Carlini, Galileo Ghini, Mino Rosi and Gianni Bertini. Also on display are the very rich plaster cast collection and paintings by Italo Griselli, one of the greatest Italian sculptor-portraitists of the first half of the twentieth century.