The Museum of Printing Arts of Jesi was established in 2000 to document the long and important typographic tradition of the city, which saw the birth of one of the first printing presses in the Marche region, and simultaneously the printing of one of the first editions of the Divine Comedy in 1472 by the typographer Federico de’ Conti. The museum is located in the sixteenth-century Palazzo Pianetti Vecchio and is developed in a large and bright hall where, in a suggestive and visually striking setting, printing presses and machines from various eras are exhibited alongside rare and valuable books. Therefore, the museum's path highlights and deepens the two aspects that characterize the invention that changed the history of human knowledge: typographic machinery and books as the final product. The exhibited volumes trace the history of printed books from incunabula to beautiful specimens from the nineteenth century, through their extrinsic features: title page, format, ornate initials, typographic marks, bindings, and illustrations. Among these, the presence of some Aldine editions, some copies of a rare collection of notices and gazettes, and almanacs, a splendid copy of the Bodonian edition of the Iliad from 1808, and others is noteworthy.

The printing presses, the printing machines, the typographic tools such as compositors, advantages, matrices, an interesting collection of movable typefaces kept in the original cases trace the history of printing from a technological point of view, from flat printing with an eighteenth-century wooden press to flat-cylindrical printing, from manual composition with movable typefaces to mechanical composition with the linotype.

All the exhibited material comes from local sources: in fact, the printing presses, machinery, and typographic tools are from Jesi typography or neighboring countries. The Museum of Printing Arts is a lively, dynamic museum with great potential; some typographic presses and art printing presses, along with the related equipment, are functional and made available to schools, for which educational workshops are offered, and to those approaching the knowledge of ancient typographic or art printing techniques (woodcut, copperplate, and lithography).

The museum also preserves the archives of the printing houses from which the exhibited machinery comes. These archives are consulted by students and scholars and are an inexhaustible documentary source of information related to public, political, and social life and private activities, linked to over 100 years of history, and more.