The noble apartment is the most prestigious part of the Palazzo Museum. The rooms present a visit path that develops two parallel and integrated reading levels. On the one hand, the frescoed decorations on the walls of the rooms, dated between the mid-fifteenth and early sixteenth centuries, the work of Giovanni del Sega and Bernardino Loschi, court painters of Alberto III Pio; on the other, the Renaissance works, formerly part of the collections of the Museums of Palazzo dei Pio, exhibited here.