The panel with the Miracle of the profaned host, painted by Paolo Uccello between 1467 and 1468, constitutes the predella of the large altarpiece depicting the Communion of the Apostles, executed by the Flemish Giusto of Ghent between 1473 and 1474. The two works were created for the Church of the Confraternita del Corpus Domini in Urbino and entered the state collections in 1861. The predella tells a story that took place in Paris around 1290 and is placed in the anti-Jewish climate of the mid-15th century which sees its birth in Italy dei Monti di Pietà, non-profit financial institutions created by some orders of friars, for the management of loans of modest amounts of money, with the aim of replacing Jewish bankers. In Urbino, in fact, the Monte di Pietà was established in 1468 at the behest of Countess Battista Sforza, Federico's wife. The story, set at night, unfolds in a fabulous way and consists of six scenes divided by twisted columns. In the first scene we see a woman who, after stealing a consecrated host, sells it to a Jewish usurer. The second depicts the moment in which the Jew and his family, after having cooked the host, witness its bleeding which recalls armed figures. In the third episode we witness the rededication of the host. In the fourth the sacrilegious woman is hanged. In the fifth, the Jew and his family are burned at the stake. In the last scene the angels and demons are represented who contend for the soul of the woman. The work is painted in the mature style of Paolo Uccello, characterized by fantastic shapes and colors and his original perspective inventions, for which even Giorgio Vasari remembers him.