Large painting from 1637, in which the artist's typical figurative composure gives way to a composition with vigorous movements and violent features, intended to evoke the mythical clash between the giant sons of the earth and the gods of Olympus. Struck by the wrath of Zeus, the giants fall overwhelmed by huge boulders. The scene is set according to a bold perspective that suggests the decoration of a ceiling, probably in a private residence. The work arrived in Pesaro with the Bolognese collection of the Hercolani acquired by the museums thanks to the legacy of Gioachino Rossini More than the other great Bolognese painters of the seventeenth century, Guido Reni represents a fundamental model for the Pesaro figurative culture of that period. A decisive influence for local artists, including the young Simone Cantarini.