It is the first easel painting documented to the painter, a masterpiece of seventeenth-century Florentine painting. The protagonist is Semiramide who is warned of the fire of Babylon and the consequent fall of the city by the squire Artace. The canvas refers to Bilivert and the late Rosselli, also showing influences of the Lorraine engravers Callot and Bellange. Theatrically set for successive floors, the scene focuses on the conversation between the two main figures, Semiramis, imposing and luminous in soft robes, and the knight, who brings her the news of the fire of Babylon.