The large canvas, the work of Emilian Camillo Procaccini (1561-1629), belongs to the Remogna collection, donated to Palazzo dei Musei between 2002 and 2013. The painting dates back to the years in which the artist moved from Emilia to Milan thanks to its first Lombard patron, Count Pirro I Visconti Borromeo, who chose it to decorate his residence outside the city of Lainate. It is not known whether the work is the one described, in 1587, by the treatise writer Giovan Paolo Lomazzo in a tercet of his Rime , which tells of a mysterious Sacrifice of Isaac painted by Procaccini for his patron. If this were the case, the painting today in Varallo would be a sort of visiting card of the pictorial skills of the young artist, who in a few years gained an absolute leading role on the Milanese scene of the late sixteenth century.