In the lunette in Carrara marble, the Madonna and Child are caught in a very sweet affectionate attitude, under an arch decorated with two winged angels. Originally the work was located in the Church of the Zitelle on Giudecca where it was part of the decoration of the main altar. In the central figures of the relief, the cultured and updated personality of the Florentine sculptor is expressed in a scene of touching intimacy that sees the Mother depicted in the act of supporting the child, supporting his back with her right hand, to return the kiss that the Child gives her. offers with great naturalness. In the very human and intimate impetus that unites the two protagonists, the virgin's left hand pushes the closed book away from itself, as if wanting to remove the already established fate from the son. The classic pose of the two angels above, languidly leaning on the cornice, underlines the vitality of the scene below. the refined management of the drapery, the monumental layout and the calibrated balance of the composition, as well as the soft rendering of the anatomies, betray a direct knowledge of Michelangelo's art, approached by the artist in his Roman stays prior to his transfer to Venice in 1527.