The museum is located in Piazza Mameli, in the ancient Borghetto, the heart of the Anghiari Renaissance, and is housed in the sixteenth-century Palazzo del Marzocco. Here are preserved precious historical and artistic testimonies, including a rare seventeenth-century work by the Flemish artist Gérard Edelinck, one of the most important copies of the legendary "Struggle for the Standard", the central scene of the original by Leonardo.

The exhibition is enriched by an innovative digital documentation system, which allows a detailed examination of the drawings and paintings inspired by Leonardo's lost fresco. Furthermore, the museum houses collections of ancient weapons, historical documents, and archaeological finds, which tell the story of Anghiari and its past as an important firearms production center in the 18th century, renowned for the sophistication of their decorations.

From the museum's panoramic terrace, you can admire the splendid landscape of the Valtiberina, while inside there is a bookshop with volumes dedicated to local history and to Leonardo da Vinci.