The Salvatore Romano Foundation is located in Florence in the central Piazza Santo Spirito .

The Salvatore Romano Foundation is located in the ancient Cenacle of the convent near the church of Santo Spirito and houses the works from the private collection of Salvatore Romano himself, from which the Foundation takes its name.

The architecture is in the Gothic style of the 1400s and preserves the imposing fresco by Andrea Orcagna which decorates the entire wall and depicts the Last Supper and the Crucifixion .

The collection includes sculptures, frescoes, fragments of architectural decoration, furnishings and finds from the Roman period . Of great importance are the "Caryatid and the Angel" by Tino di Camaino and two figures of saints that were attributed to Donatello . Thanks to Salvatore Romano 's legacy it was possible to create the Museum and make his works of art and pieces of history usable. Inside the Cenacle there is also his tomb, in the same place where his collections are exhibited.