The young man in armor on the right is Perseus, represented while he is recovering after having saved Andromeda, lying on the left. The young woman had been sacrificed to the sea monster depicted, petrified, below her, as punishment for the pride of her mother Cassiopeia. The painting also narrates the mythological origin of the coral, born from algae soaked in the blood of the monster and turned into stone in contact with the head of the Medusa, depicted in the lower centre. The sea creatures surrounding Perseus and Andromeda play with the corals, joyfully amazed at this transformation.

The canvas sanctions the handover from the generation of Gregorio, with a Baroque imprint, to that of his son Lorenzo, distinguished by more elegant and composed, typical of the eighteenth century.