The altarpiece, carved in high relief in painted and gilded wood, depicts the Lamentation over the dead Christ: in the foreground the Virgin is seated in the act of holding the reclining body of Christ on her knees, whose right arm descends to the ground. On the left, St. John the Evangelist and Mary Magdalene support Christ's head; on the right appears San Giuseppe d'Arimatea with the characteristic turban. The high relief is attributed to Paolo Campsa, an Istrian sculptor active in Venice between the 15th and 16th centuries, author of altars in the church of Santa Maria Assunta in Torcello, and is dated between 1505 and 1514.